8 Health Benefits of Tocotrienol-Only Vitamin E by Dr Barrie Tan

Dr barrie tan

Dr Barrie Tan is a name that resonates with authority and expertise in nutrition and health. As the world’s foremost expert on vitamin E, Dr Tan has significantly contributed to understanding the health benefits of Tocotrienols. In this blog, we’ll explore the life and work of Dr Barrie Tan and learn the truth about vitamin E.

Background Information – Who is Dr Barrie Tan?

With over 30 years of experience, Dr Tan’s extensive research has significantly contributed to understanding Vitamin E, particularly tocotrienols.

Dr Tan’s work has led to the discovery of tocotrienols from sources like Palm oil, Rice, and Annatto. He has made groundbreaking discoveries, especially identifying the most potent forms of Vitamin E: Delta and Gamma Tocotrienols.

His research into the Annatto plant in South America, a vibrant condiment derived from the seeds of the Achiote tree, led to the discovery of the purest and most potent form of Vitamin E antioxidant called tocotrienols.

Dr Tan refers to the Annatto plant as a ‘One Plant Wonder’ due to its unique property of containing 100% tocotrienols, free of tocopherols that can interfere with lipid absorption and metabolism.

DeltaGold® Technology by Dr Barrie Tan

Dr Barrie Tan has developed an affordable and eco-friendly technique to extract Tocotrienols from the Annatto plant without harsh or synthetic chemicals, petrochemicals, or solvents. The DeltaGold® technology, developed by Dr Barrie Tan, features several key aspects that make it unique and effective:

  1. Patented Extraction Process: The DeltaGold® technology involves a patented process to extract Tocotrienols from the Annatto plant, which is the only known source of 100% pure Tocotrienols. This method ensures that the product is free from adulteration.
  2. Tocopherol-Free: The DeltaGold® Vitamin E is free from Tocopherols. Research has shown that Tocopherols can interfere with the absorption of Tocotrienols, making Tocotrienol-based products like DeltaGold® more effective.
  3. Sourced from Annatto Plant: The tocotrienols in DeltaGold® are derived exclusively from the Annatto plant. This plant-based source contains only Tocotrienols, with no Tocopherols present.
  4. High Purity and Potency: The extraction method used in DeltaGold® ensures high purity and potency in the Tocotrienols. This ensures that the final product delivers the full benefits of this potent form of Vitamin E.
  5. Scientifically Supported: The efficacy of DeltaGold® Tocotrienols is supported by extensive research and clinical trials. These studies have demonstrated significant health benefits, including lipid reduction, liver protection, and potential enhancement of survival rates in chronic conditions.

Studies Conducted on Tocotrienol Only Vitamin E Supplementation

Dr Barrie Tan’s extensive research on tocotrienols, a form of vitamin E, has shed light on their incredible health benefits. Numerous studies have been conducted to understand the potential of tocotrienol-only vitamin E in promoting overall well-being.

Let’s explore the various studies on the effects of tocotrienol-only vitamin E on health conditions.

1. Tocotrienols Only Form of Vitamin E – The Discovery

One of Dr Tan’s most groundbreaking contributions is the discovery of tocotrienols. Vitamin E is a vital fat-soluble nutrient known for its antioxidant properties, crucial for maintaining health and preventing diseases. It comes in two primary forms: tocotrienols and tocopherols, each with distinct benefits.

In simple terms, Tocotrienol is a highly effective form of vitamin E. It has a unique ability to quickly enter and work within cells, making it especially beneficial for heart health, blood sugar control, and overall skin and brain well-being.

Tocopherol, while valuable and has its benefits, such as skin and hair health benefits, doesn’t have this rapid action. So, for superior health benefits, tocotrienol is the preferred choice.

2. Tocotrienols and Cancer Clinical Trials

As per the latest literature, Tocotrienols may contain cancer-killing features that target cancer cells by inhibiting NF-KAPPA B, a key cancer-promoting protein. This inhibition triggers apoptosis, causing cancer cells to self-destruct.

Furthermore, tocotrienols have been shown to reduce angiogenesis; the process tumors use to grow new blood vessels, effectively starving them of the nutrients needed to fuel their growth.

Clinical and pre-clinical studies have demonstrated tocotrienols’ efficacy in ovarian, pancreatic, breast, prostate, lung, colon, liver, and skin cancer.

3. Tocotrienols and Cardiovascular Health

The heart is the lifeline of our body, beating about 2.5 billion times in an average lifetime. Dr Barrie Tan’s research shows that tocotrienols support cardiovascular health.[1] These compounds lower total cholesterol, LDL cholesterol, and triglycerides.

They also inhibit inflammation, reduce C-reactive protein (CRP), increase the body’s natural antioxidant capacity, lower blood pressure, and improve arterial function. Additionally, tocotrienols have demonstrated the ability to regress atherosclerosis by preventing plaque formation and improving the integrity and stability of existing plaques.

4. The Osteoporosis Connection

As we age, our bones naturally weaken. Osteoporosis, a condition that affects many, especially women, is a major concern. The latest research reveals that tocotrienols promote bone turnover, increase bone calcium content, and resist bone loss, particularly in postmenopausal osteopenia subjects. [2]

These benefits extend to both women and men, as preclinical studies suggest that tocotrienols can prevent bone loss and maintain bone strength. Tocotrienols’ anti-inflammatory and antioxidant properties play a significant role in supporting bone health.

5. Battling Fatty Liver Disease with Annatto Tocotrienols

Nonalcoholic fatty liver disease (NAFLD) is a growing concern, affecting millions of Americans. Dr Tan’s work highlights the effectiveness of Annatto tocotrienols in reducing fat and enzymes in the liver, as well as decreasing liver inflammation.[3]

These tocotrienols have demonstrated the ability to lower weight and BMI in overweight NAFLD patients and reduce the Fatty Liver Index. Considering the limited treatment options for NAFLD, tocotrienols, and especially delta- and gamma-tocotrienols, emerge as a promising solution.

6. Tocotrienols Powerful Antioxidant for Cell Health

Cell health is the foundation of overall well-being, and the latest research underscores the importance of tocotrienols. These compounds help maintain cell membrane integrity, protect cell membrane lipids from oxidation, and are 50 times more effective as antioxidants than alpha-tocopherol.[4]

This superior antioxidant capacity is due to the unique structure of tocotrienols, which enables them to capture oxygen radicals at an astonishing speed.

7. Keep Inflammation at Bay with Vitamin E

Chronic inflammation is a root cause of many health conditions, including cardiovascular disease. Dr Barrie Tan’s work emphasizes the anti-inflammatory properties of tocotrienols. These compounds reduce prominent markers of inflammation, such as CRP, and strongly inhibit inflammatory responses.

Moreover, they promote the function of cells that destroy damaged tissue and enhance the immune system’s ability to fight inflammation. Tocotrienols directly block inflammatory pathways through a steroid-like anti-inflammatory mechanism, making them a valuable addition to anti-inflammatory regimens.[5]

8. Tocotrienols for Metabolic Health

Tocotrienols have shown significant promise in enhancing metabolic health, particularly in regulating lipids. Their role in influencing lipid metabolism is pivotal, especially in acting as agonists for energy metabolism regulators, which are essential in managing conditions like diabetes, obesity, and atherosclerosis.

Notably, tocotrienol-rich fraction (TRF) supplementation has demonstrated substantial improvements in muscle metabolomes in animal studies, indicating a boost in lipid metabolism. This benefit could extend to age-related metabolic disorders.

Furthermore, tocotrienols effectively improve metabolic syndrome by enhancing lipid profiles, reducing atherosclerotic lesions, and normalizing blood pressure. Their anti-inflammatory and antioxidant properties further contribute to their potential in managing metabolic diseases.

Ebook- The Truth About Vitamin E’ by Dr Barrie Tan

To learn in depth about the research of Dr Barrie Tan on Tocotrienols, you can read, “The Truth about Vitamin E”. In his enlightening ebook, “The Truth About Vitamin E,” Dr Barrie Tan delves into the complexities and misconceptions surrounding Vitamin E, a crucial nutrient for our health.

With his extensive research and expertise, Dr Tan uncovers the lesser-known aspects of Vitamin E, particularly focusing on Tocotrienols. He distinguishes between Tocotrienols and the more commonly known Tocopherols, emphasizing the former’s superior health benefits.

This book is an eye-opener, shedding light on how Tocotrienols, especially from the Annatto plant, play a pivotal role in combating oxidative stress and supporting various aspects of health, from cardiovascular to metabolic wellness.

Dr Tan’s insights provide invaluable guidance for anyone looking to understand the true potential of Vitamin E in their health regimen.


Dr Barrie Tan’s journey into nutrition and health has been remarkable. His discoveries in tocotrienols have opened new doors in the quest for better health. The potential of tocotrienols, especially Annatto tocotrienols, in addressing cancer, cardiovascular health, bone health, and inflammation is truly exciting.

Dr Barrie Tan’s dedication to the cause of health and his line of innovative products serve as a beacon of hope for individuals seeking improved well-being. In the realm of nutrition, Dr Barrie Tan is a name that will continue to inspire and lead the way for future generations.

Health Benefits of Tocotrienol-Only Vitamin E – Frequently Asked Questions (FAQs)

Who discovered tocotrienol?

The discovery of tocotrienol is credited to Dr Barrie Tan, a renowned expert in vitamin E research. His groundbreaking work identifying and understanding tocotrienols has significantly advanced our knowledge.

Are tocotrienols good for you?

Yes, tocotrienols benefit health, offering antioxidant properties crucial for maintaining overall well-being. Dr Barrie Tan’s research highlights tocotrienols’ effectiveness in promoting heart health, blood sugar control, and skin and brain health.

What are the benefits of annatto tocotrienols?

Annatto tocotrienols, a focus of Dr Barrie Tan’s research, are known for their powerful health benefits. They aid in cardiovascular health, support bone health, combat fatty liver disease, and offer significant antioxidant and anti-inflammatory properties.

Who is the father of vitamin E?

Dr Barrie Tan is often regarded as the father of vitamin E Tocotrienol due to his extensive research and discoveries in the field, particularly his groundbreaking work on tocotrienols.

What are the 4 tocotrienols?

The four tocotrienols are alpha, beta, gamma, and delta tocotrienols. Each has unique benefits, with research by Dr Barrie Tan emphasizing their significant health-promoting properties.

What is the magic of vitamin E?

The “magic” of vitamin E, particularly tocotrienols, lies in their potent antioxidant properties and their ability to support various aspects of health, as demonstrated in the research of Dr Barrie Tan.

What is the nickname for vitamin E?

Vitamin E is sometimes referred to as the “skin vitamin” due to its beneficial effects on skin health. Dr Barrie Tan’s research on tocotrienols, a form of vitamin E, further highlights their health benefits.

Which tocotrienol is best?

According to Dr Barrie Tan’s research, the best tocotrienol may depend on the specific health benefits sought. Delta- and gamma-tocotrienols, often highlighted in his work, are particularly noted for their potent effects.

Can you take tocotrienols every day?

Yes, it’s generally safe to take tocotrienols daily. Dr Barrie Tan’s research supports the regular consumption of tocotrienols as part of a healthy diet, given their beneficial properties for overall well-being.

Are tocotrienols good for kidneys?

Tocotrienols may have positive effects on kidney health due to their antioxidant properties. Dr Barrie Tan’s research suggests that tocotrienols can be beneficial in protecting against oxidative stress, which is advantageous for kidney function.

Is tocotrienols good for the liver?

Yes, tocotrienols, particularly Annatto tocotrienols researched by Dr Barrie Tan, are beneficial for liver health. They have been shown to reduce liver fat and enzymes, thereby aiding in the management of nonalcoholic fatty liver disease (NAFLD).

What is the difference between vitamin E and tocotrienols?

Vitamin E is a group of eight fat-soluble compounds, including tocopherols and tocotrienols. Dr Barrie Tan’s research focuses on tocotrienols, distinguished by their chemical structure and superior health benefits compared to tocopherols.

Can vitamin E reverse fatty liver?

Annatto tocotrienols, as researched by Dr Barrie Tan, have shown promise in aiding the reversal of fatty liver, especially in nonalcoholic fatty liver disease (NAFLD) cases. These tocotrienols help reduce liver fat and inflammation, improving liver health.


  1. Benson D. Barrie Tan, PhD: Using Tocotrienols to Address Lifestyle and Metabolic Disease. Integr Med (Encinitas). 2019 Apr;18(2):26-27.
  2. Passwater, Richard A. “Tocotrienols: Emerging Science and Innovations of Vitamin E Part 4: A Review of Groundbreaking Tocotrienol Research.”
  3. Zainal, Zaida, et al. “Therapeutic potential of palm oil vitamin E-derived tocotrienols in inflammation and chronic diseases: Evidence from preclinical and clinical studies.” Food Research International 156 (2022): 111175.
  4. Aggarwal, Vaishali, et al. “Molecular mechanisms of action of tocotrienols in cancer: Recent trends and advancements.” International journal of molecular sciences 20.3 (2019): 656.
  5. Zhao, Lu, et al. “Muscadine grape seed oil as a novel source of tocotrienols to reduce adipogenesis and adipocyte inflammation.” Food & function 6.7 (2015): 2293-2302.

Disclaimer: This content, including advice, provides generic information only. It is not a substitute for a qualified medical opinion. Always consult a specialist or your own doctor for more information. Ingredient Fact does not claim responsibility for this information.

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